The role of the G6PD AEth376G/968C allele in glucose-6-phosphate dehydrogenase deficiency in the seerer population of Senegal.

نویسندگان

  • Carla De Araujo
  • Florence Migot-Nabias
  • Juliette Guitard
  • Stéphane Pelleau
  • Tom Vulliamy
  • Rolande Ducrocq
چکیده

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is common in tropical Sub-Saharan countries. The allele most frequently associated with G6PD deficiency in this a region is G6PD 376G/202A. Here, we show that, the prevalence of G6PD deficiency is 12% in the Sereer ethnic group from Senegal ant that the 376G/968C genotype is predominant; the frequency of the 376G/202A genotype is very low in this ethnic group.

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عنوان ژورنال:
  • Haematologica

دوره 91 2  شماره 

صفحات  -

تاریخ انتشار 2006